User profiles for Sergio A. Acuna

Sergio A Acuna

University of Toronto
Verified email at utoronto.ca
Cited by 3275

A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta …

F Dossa, TR Chesney, SA Acuna… - The lancet …, 2017 - thelancet.com
Background A watch-and-wait approach for patients with clinical complete response to
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal cancer. …

Opioid use after discharge in postoperative patients: a systematic review

…, TR Chesney, S Srikandarajah, SA Acuna… - Annals of …, 2018 - journals.lww.com
Background: Over the past 2 decades, there has been an increase in opioid use and
subsequently, opioid deaths. The amount of opioid prescribed to surgical patients has also …

Cancer mortality among recipients of solid-organ transplantation in Ontario, Canada

SA Acuna, KA Fernandes, C Daly, LK Hicks… - JAMA …, 2016 - jamanetwork.com
Importance Solid-organ transplant recipients (SOTRs) are at greater risk of developing some
cancers than the general population; however, because they are also at increased risk of …

Association between adjuvant chemotherapy and overall survival in patients with rectal cancer and pathological complete response after neoadjuvant chemotherapy …

F Dossa, SA Acuna, AS Rickles, M Berho… - JAMA …, 2018 - jamanetwork.com
Importance Although American guidelines recommend use of adjuvant chemotherapy in
patients with locally advanced rectal cancer, individuals who achieve a pathological complete …

Laparoscopic and robotic hysterectomy in endometrial cancer patients with obesity: a systematic review and meta-analysis of conversions and complications

…, F Dossa, V Liani, Y Kaur, SA Acuna… - American journal of …, 2019 - Elsevier
Objective Data Robotic assistance may facilitate completion of minimally invasive hysterectomy,
which is the standard of care for the treatment of early-stage endometrial cancer, in …

[HTML][HTML] Harmful or physiologic: diagnosing fibrinolysis shutdown in a trauma cohort with rotational thromboelastometry

JC Gomez-Builes, SA Acuna, B Nascimento… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: Despite its central role in early trauma coagulopathy, abnormal fibrinolysis
continues to be poorly understood. Excessive fibrinolysis is a known contributor to mortality. …

Preoperative localization of colorectal cancer: a systematic review and meta-analysis

SA Acuna, M Elmi, PS Shah, NG Coburn… - Surgical …, 2017 - Springer
Background Preoperative colorectal tumor localization is crucial for appropriate resection
and treatment planning. As the localization accuracy of conventional colonoscopy is …

[HTML][HTML] Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques

L Evgin, SA Acuna, CT De Souza, M Marguerie… - Molecular Therapy, 2015 - cell.com
Oncolytic viruses (OVs) have shown promising clinical activity when administered by direct
intratumoral injection. However, natural barriers in the blood, including antibodies and …

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

JG Pol, SA Acuna, B Yadollahi, N Tang… - …, 2019 - Taylor & Francis
Multiple immunotherapeutics have been approved for cancer patients, however advanced
solid tumors are frequently refractory to treatment. We evaluated the safety and …

Outcomes of solid organ transplant recipients with preexisting malignancies in remission: a systematic review and meta-analysis

SA Acuna, JW Huang, C Daly, PS Shah, SJ Kim… - …, 2017 - journals.lww.com
Background Solid organ transplant recipients (SOTR) with a pretransplant malignancy (PTM)
are at increased risk for cancer recurrence. However, it is unclear whether differences in …