User profiles for Sergio A. Acuna
Sergio A AcunaUniversity of Toronto Verified email at utoronto.ca Cited by 3275 |
A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta …
Background A watch-and-wait approach for patients with clinical complete response to
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal cancer. …
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal cancer. …
Opioid use after discharge in postoperative patients: a systematic review
…, TR Chesney, S Srikandarajah, SA Acuna… - Annals of …, 2018 - journals.lww.com
Background: Over the past 2 decades, there has been an increase in opioid use and
subsequently, opioid deaths. The amount of opioid prescribed to surgical patients has also …
subsequently, opioid deaths. The amount of opioid prescribed to surgical patients has also …
Cancer mortality among recipients of solid-organ transplantation in Ontario, Canada
Importance Solid-organ transplant recipients (SOTRs) are at greater risk of developing some
cancers than the general population; however, because they are also at increased risk of …
cancers than the general population; however, because they are also at increased risk of …
Association between adjuvant chemotherapy and overall survival in patients with rectal cancer and pathological complete response after neoadjuvant chemotherapy …
Importance Although American guidelines recommend use of adjuvant chemotherapy in
patients with locally advanced rectal cancer, individuals who achieve a pathological complete …
patients with locally advanced rectal cancer, individuals who achieve a pathological complete …
Laparoscopic and robotic hysterectomy in endometrial cancer patients with obesity: a systematic review and meta-analysis of conversions and complications
Objective Data Robotic assistance may facilitate completion of minimally invasive hysterectomy,
which is the standard of care for the treatment of early-stage endometrial cancer, in …
which is the standard of care for the treatment of early-stage endometrial cancer, in …
[HTML][HTML] Harmful or physiologic: diagnosing fibrinolysis shutdown in a trauma cohort with rotational thromboelastometry
JC Gomez-Builes, SA Acuna, B Nascimento… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: Despite its central role in early trauma coagulopathy, abnormal fibrinolysis
continues to be poorly understood. Excessive fibrinolysis is a known contributor to mortality. …
continues to be poorly understood. Excessive fibrinolysis is a known contributor to mortality. …
Preoperative localization of colorectal cancer: a systematic review and meta-analysis
SA Acuna, M Elmi, PS Shah, NG Coburn… - Surgical …, 2017 - Springer
Background Preoperative colorectal tumor localization is crucial for appropriate resection
and treatment planning. As the localization accuracy of conventional colonoscopy is …
and treatment planning. As the localization accuracy of conventional colonoscopy is …
[HTML][HTML] Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques
Oncolytic viruses (OVs) have shown promising clinical activity when administered by direct
intratumoral injection. However, natural barriers in the blood, including antibodies and …
intratumoral injection. However, natural barriers in the blood, including antibodies and …
Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials
Multiple immunotherapeutics have been approved for cancer patients, however advanced
solid tumors are frequently refractory to treatment. We evaluated the safety and …
solid tumors are frequently refractory to treatment. We evaluated the safety and …
Outcomes of solid organ transplant recipients with preexisting malignancies in remission: a systematic review and meta-analysis
SA Acuna, JW Huang, C Daly, PS Shah, SJ Kim… - …, 2017 - journals.lww.com
Background Solid organ transplant recipients (SOTR) with a pretransplant malignancy (PTM)
are at increased risk for cancer recurrence. However, it is unclear whether differences in …
are at increased risk for cancer recurrence. However, it is unclear whether differences in …