Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome

JC Marshall, DJ Cook, NV Christou… - Critical care …, 1995 - journals.lww.com
… MD MSc, FRCPC; Christou, Nicolas V. MD PhD, FCCM; Bernard, Gordon R. MD; Sprung,
Charles L. … Christou); Department of Medicine, Vanderbilt University, Nashville, TN (Dr …

Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients

NV Christou, JS Sampalis, M Liberman, D Look… - Annals of …, 2004 - journals.lww.com
Objective: This study tested the hypothesis that weight-reduction (bariatric) surgery reduces
long-term mortality in morbidly obese patients. Background: Obesity is a significant cause of …

Efficacy and safety of monoclonal antibody to human tumor necrosis factor α in patients with sepsis syndrome: a randomized, controlled, double-blind, multicenter …

…, R Oser, D Gilbert, JE Leggett, K Waite, NV Christou… - Jama, 1995 - jamanetwork.com
Objective. —To evaluate the efficacy and safety of anti—tumor necrosis factor α monoclonal
antibody (TNF-α MAb) in the treatment of patients with sepsis syndrome. Design. —…

Weight gain after short-and long-limb gastric bypass in patients followed for longer than 10 years

NV Christou, D Look, LD MacLean - Annals of surgery, 2006 - journals.lww.com
Objective: To complete a long-term (> 10 years) follow-up of patients undergoing isolated
roux-en-Y gastric bypass for severe obesity. Background: Long-term results of gastric bypass …

The gastrointestinal tract. The" undrained abscess" of multiple organ failure.

JC Marshall, NV Christou, JL Meakins - Annals of surgery, 1993 - ncbi.nlm.nih.gov
OBJECTIVE: This study determined the association between proximal gastrointestinal (GI)
colonization and the development of intensive care unit (ICU)-acquired infection and multiple …

Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems

AJE Seely, NV Christou - Critical care medicine, 2000 - journals.lww.com
… Seely and Christou) and Surgical Critical Care (Dr. Christou), Royal Victoria Hospital,
McGill University Health Center, Montreal, Canada. … Ahmed NA, Christou NV, Meakins JL …

Bariatric surgery reduces cancer risk in morbidly obese patients

NV Christou, M Lieberman, F Sampalis… - Surgery for obesity and …, 2008 - Elsevier
BACKGROUND: To assess the effect of bariatric surgery on the cancer risk of patients with
morbid obesity because evidence is mounting of an association between obesity and cancer. …

The microbiology of multiple organ failure: the proximal gastrointestinal tract as an occult reservoir of pathogens

JC Marshall, NV Christou, R Horn… - Archives of …, 1988 - jamanetwork.com
• The microbiology of infection acquired in the intensive care unit (ICU) was studied prospectively
in 205 consecutive patients admitted to a surgical intensive care unit. A multiple organ …

Surgical Infection Society intra-abdominal infection study: prospective evaluation of management techniques and outcome

NV Christou, PS Barie, EP Dellinger… - Archives of …, 1993 - jamanetwork.com
• This prospective, open, consecutive, nonrandomized trial examined management techniques
and outcome in severe peritonitis. A total of 239 patients with surgical infection in the …

The impact of weight reduction surgery on health-care costs in morbidly obese patients

JS Sampalis, M Liberman, S Auger, NV Christou - Obesity surgery, 2004 - Springer
Background: The treatment of obesity and related comorbidities are significant financial
burdens and sources of resource expenditure. This study was conducted in order to assess the …