User profiles for Muriel Brackstone

Muriel Brackstone

Professor of Surgery, Western University
Verified email at lhsc.on.ca
Cited by 4393

Computational radiology in breast cancer screening and diagnosis using artificial intelligence

…, FI Lu, S Gandhi, N Meti, M Brackstone… - Canadian …, 2021 - journals.sagepub.com
Breast cancer screening has been shown to significantly reduce mortality in women. The
increased utilization of screening examinations has led to growing demands for rapid and …

The microbiota of breast tissue and its association with breast cancer

C Urbaniak, GB Gloor, M Brackstone… - Applied and …, 2016 - Am Soc Microbiol
In the United States, 1 in 8 women will be diagnosed with breast cancer in her lifetime. Along
with genetics, the environment contributes to disease development, but what these exact …

Locoregional therapy of locally advanced breast cancer: a clinical practice guideline

M Brackstone, GG Fletcher, IS Dayes, Y Madarnas… - Current …, 2015 - mdpi.com
Questions:(1) In female patients with locally advanced breast cancer (labc) and good
response to neoadjuvant chemotherapy (nact), including endocrine therapy, what is the role of …

Incisional negative pressure wound therapy decreases the frequency of postoperative perineal surgical site infections: a cohort study

…, B Kidane, K Britto, M Brackstone… - Diseases of the colon …, 2014 - journals.lww.com
BACKGROUND: Abdominoperineal resection is a procedure associated with high rates of
perineal surgical site infections, causing distress to the patient, costs to the hospital system, …

[HTML][HTML] A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local …

S Gandhi, M Brackstone, NJL Hong, D Grenier… - Breast cancer research …, 2022 - Springer
Purpose The neoadjuvant treatment of breast cancer (NABC) is a rapidly changing area that
benefits from guidelines integrating evidence with expert consensus to help direct practice. …

Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study

…, S Meterissian, A Arnaout, M Brackstone… - Journal of Clinical …, 2015 - ascopubs.org
Purpose An increasing proportion of patients (> 30%) with node-positive breast cancer will
obtain an axillary pathologic complete response after neoadjuvant chemotherapy (NAC). If …

Microbiota of human breast tissue

C Urbaniak, J Cummins, M Brackstone… - Applied and …, 2014 - Am Soc Microbiol
In recent years, a greater appreciation for the microbes inhabiting human body sites has
emerged. In the female mammary gland, milk has been shown to contain bacterial species, …

Management of the axilla in early-stage breast cancer: Ontario Health (Cancer Care Ontario) and ASCO guideline

M Brackstone, FG Baldassarre… - Journal of Clinical …, 2021 - ingentaconnect.com
PURPOSE To provide recommendations on the best strategies for the management and on
the best timing and treatment (surgical and radiotherapeutic) of the axilla for patients with …

[HTML][HTML] Tumour dormancy in breast cancer: an update

M Brackstone, JL Townson, AF Chambers - Breast Cancer Research, 2007 - Springer
Delayed recurrences, common in breast cancer, are well explained by the concept of tumour
dormancy. Numerous publications describe clinical times to disease recurrence or death, …

CYP3A4 and seasonal variation in vitamin D status in addition to CYP2D6 contribute to therapeutic endoxifen level during tamoxifen therapy

…, J Younus, TA Vandenberg, M Brackstone… - Breast cancer research …, 2013 - Springer
Tamoxifen is a widely utilized adjuvant anti-estrogen agent for hormone receptor-positive
breast cancer, known to undergo CYP2D6-mediated bioactivation to endoxifen. However, little …