Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms

CH Tator, MG Fehlings - Journal of neurosurgery, 1991 - thejns.org
✓ In patients with spinal cord injury, the primary or mechanical trauma seldom causes total
transection, even though the functional loss may be complete. In addition, biochemical and …

Traumatic spinal cord injury

…, M Kotter, C Druschel, A Curt, MG Fehlings - Nature reviews Disease …, 2017 - nature.com
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social
and vocational well-being of patients. The demographic of SCIs is shifting such that an …

Efficacy and safety of surgical decompression in patients with cervical spondylotic myelopathy: results of the AOSpine North America prospective multi-center study

MG Fehlings, JR Wilson, B Kopjar, ST Yoon, PM Arnold… - JBJS, 2013 - journals.lww.com
Background: Cervical spondylotic myelopathy is the leading cause of spinal cord
dysfunction worldwide. The objective of this study was to evaluate the impact of surgical …

Epidemiology, demographics, and pathophysiology of acute spinal cord injury

LHS Sekhon, MG Fehlings - Spine, 2001 - journals.lww.com
Spinal cord injury occurs through various countries throughout the world with an annual
incidence of 15 to 40 cases per million, with the causes of these injuries ranging from motor …

A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group

…, CI Shaffrey, SH Berven, JS Harrop, MG Fehlings… - Spine, 2010 - journals.lww.com
Study Design. Systematic review and modified Delphi technique. Objective. To use an
evidence-based medicine process using the best available literature and expert opinion …

A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status

…, R Hedlund, J Harrop, M Dvorak, K Wood, MG Fehlings… - Spine, 2005 - journals.lww.com
Study Design. A new proposed classification system for thoracolumbar (TL) spine injuries,
including injury severity assessment, designed to assist in clinical management. Objective. To …

Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)

MG Fehlings, A Vaccaro, JR Wilson, A Singh… - PloS one, 2012 - journals.plos.org
Background There is convincing preclinical evidence that early decompression in the setting
of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early …

Global prevalence and incidence of traumatic spinal cord injury

…, S Kalsi-Ryan, A Nouri, MG Fehlings - Clinical …, 2014 - Taylor & Francis
Background Spinal cord injury (SCI) is a traumatic event that impacts a patient’s physical,
psychological, and social well-being and places substantial financial burden on health care …

Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon

JW Rowland, GWJ Hawryluk, B Kwon, MG Fehlings - Neurosurgical focus, 2008 - thejns.org
This review summarizes the current understanding of spinal cord injury pathophysiology
and discusses important emerging regenerative approaches that have been translated into …

Degenerative cervical myelopathy: epidemiology, genetics, and pathogenesis

…, L Tetreault, A Singh, SK Karadimas, MG Fehlings - Spine, 2015 - journals.lww.com
Study Design. Review. Objective. To formally introduce “degenerative cervical myelopathy”(DCM)
as the overarching term to describe the various degenerative conditions of the cervical …