Valve-sparing root replacement compared with composite valve graft procedures in patients with aortic root dilation

M Ouzounian, V Rao, C Manlhiot, N Abraham… - Journal of the American …, 2016 - jacc.org
Background : Although aortic valve-sparing (AVS) operations are established alternatives to
composite valve graft (CVG) procedures for patients with aortic root aneurysms, comparative …

Cardiovascular proteomics: tools to develop novel biomarkers and potential applications

…, T Kislinger, B Stanley, J van Eyk, M Ouzounian… - Journal of the American …, 2006 - jacc.org
Proteomics is the new systems biological approach to the study of proteins and protein
variation on a large scale as a result of biological processes and perturbations. The field is …

Diastolic heart failure: mechanisms and controversies

M Ouzounian, DS Lee, PP Liu - Nature Clinical Practice Cardiovascular …, 2008 - nature.com
Epidemiological and experimental studies have documented both the rising burden of
diastolic heart failure (DHF) and several mechanisms that distinguish this disease from systolic …

2021 The American Association for Thoracic Surgery expert consensus document: surgical treatment of acute type A aortic dissection

…, TG Gleason, Y Okita, M Ouzounian… - The Journal of thoracic …, 2021 - jtcvs.org
Acute aortic dissection (AD) involves the ascending aorta in approximately two-thirds of patients.
1, 2 Chest pain is the most common feature, but clinical presentation can be varied, and …

Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth

…, R Khattar, K Farrokhi, J Byrne, M Ouzounian… - Nature …, 2016 - nature.com
Resident macrophages densely populate the normal arterial wall, yet their origins and the
mechanisms that sustain them are poorly understood. Here we use gene-expression profiling …

Biomechanics of aortic dissection: a comparison of aortas associated with bicuspid and tricuspid aortic valves

…, J Butany, CA Simmons, M Ouzounian - Journal of the …, 2020 - Am Heart Assoc
Background Current methods for aortic dissection risk assessment are inadequate for patients
with ascending aortic aneurysms associated with either bicuspid aortic valves (BAVs) or …

[HTML][HTML] A progress report on reimplantation of the aortic valve

TE David, CM David, M Ouzounian, CM Feindel… - The Journal of thoracic …, 2021 - Elsevier
Objective To examine the late outcomes of reimplantation of the aortic valve (RAV) in patients
followed prospectively since surgery. Methods All 465 patients who had RAV from 1989 to …

Open aortic arch repair: state-of-the-art and future perspectives

M Ouzounian, SA LeMaire, JS Coselli - Seminars in thoracic and …, 2013 - Elsevier
Surgical procedures for the treatment of complex aortic arch pathology remain among the
most challenging cardiovascular operations, incurring considerable risk for death and stroke. …

[HTML][HTML] Systematic review of contemporary outcomes of endovascular and open thoracoabdominal aortic aneurysm repair

…, M Al-Omran, TL Forbes, M Ouzounian - Journal of vascular …, 2020 - Elsevier
Objective The purpose of the study was to provide a systematic review of the literature
reporting the contemporary early outcomes after endovascular and open repair of …

Sex-related differences in patients undergoing thoracic aortic surgery: evidence from the Canadian Thoracic Aortic Collaborative

J Chung, LM Stevens, M Ouzounian, I El-Hamamsy… - Circulation, 2019 - Am Heart Assoc
Background: Contemporary outcomes after surgical management of thoracic aortic disease
have improved; however, the impact of sex-related differences is poorly understood. Methods…