Objectives To examine the effects of aerobic exercise on cognition and other biomarkers
associated with Alzheimer disease pathology for older adults with mild cognitive impairment, …

Objective To examine the effects of intranasal insulin administration on cognition, function,
cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild …

Background: Reduced brain insulin signaling and low CSF-to-plasma insulin ratios have been
observed in patients with Alzheimer disease (AD). Furthermore, intracerebroventricular or …

Objective Insulin resistance (impaired insulin action) has been associated with Alzheimer
disease (AD) and memory impairment, independent of AD. Peroxisome proliferator-activated …

Background: Insulin resistance is a causal factor in prediabetes (PD) and type 2 diabetes (T2D)
and increases the risk of developing Alzheimer disease (AD). Reductions in cerebral …

Glucose is the brain’s principal energy substrate. In Alzheimer’s disease (AD), there
appears to be a pathological decrease in the brain’s ability to use glucose. Neurobiological …

The decision to vote has puzzled scholars for decades. Theoretical models predict little or no
variation in participation in large population elections and empirical models have typically …

Intranasal insulin administration raises central nervous system (CNS) insulin levels in humans
and acutely facilitates verbal memory in patients with Alzheimer’s disease (AD), an effect …

Previous trials have shown promising effects of intranasally administered insulin for adults
with Alzheimer’s disease dementia (AD) or amnestic mild cognitive impairment (MCI). These …

Mass spectrometric analysis of human plasma and urine revealed abundant nitrated
derivatives of all principal unsaturated fatty acids. Nitrated palmitoleic, oleic, linoleic, linolenic, …