Background Patients with familial adenomatous polyposis have a nearly 100 percent risk of
colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal …

… To do so, Karen King says, we must first disentangle modern historiography from the …
King shows how historians have been misled by ancient Christian polemicists who attacked …

Nucleoside analogs are important components of treatment regimens for various malignancies.
Nucleoside-specific membrane transporters mediate plasma membrane permeation of …

Biopsies of ABO-incompatible and positive crossmatch (HLA-incompatible) renal allografts
were retrospectively examined to compare results of C4d and C3d staining, and the …

BACKGROUND: The incidence of allergic transfusion reactions (ATRs) ranges from 1% to 3%
of all transfusions, and they are difficult to prevent. This study evaluated whether removing …

Purpose National Surgical Adjuvant Breast and Bowel Project (NSABP) Protocol B-18 was
designed to determine whether four cycles of doxorubicin and cyclophosphamide (AC) …

Understanding the genetic structure of human populations is of fundamental interest to
medical, forensic and anthropological sciences. Advances in high-throughput genotyping …

Tumor angiogenesis is mediated by tumor-secreted angiogenic growth factors that interact
with their surface receptors expressed on endothelial cells. Vascular endothelial growth factor …

Background More than 20,000 candidates for kidney transplantation in the United States
are sensitized to HLA and may have a prolonged wait for a transplant, with a reduced …

Background. Hyperacute rejection (HAR) and acute humoral rejection (AHR) remain recalcitrant
conditions without effective treatments, and usually result in graft loss. Plasmapheresis (…