Imaging brain activity during seizures in freely behaving rats using a miniature multi-modal imaging system
…, MM Koletar, D Ringuette, R Gad, M Jeffrey… - Biomedical Optics …, 2016 - opg.optica.org
We report on a miniature label-free imaging system for monitoring brain blood flow and
blood oxygenation changes in awake, freely behaving rats. The device, weighing 15 grams, …
blood oxygenation changes in awake, freely behaving rats. The device, weighing 15 grams, …
Acute administration of docosahexaenoic acid increases resistance to pentylenetetrazol-induced seizures in rats
AY Taha, MA Jeffrey, NMY Taha, S Bala… - Epilepsy & Behavior, 2010 - Elsevier
OBJECTIVE: Docosahexaenoic acid (DHA), an omega-3 fatty acid, has been reported to raise
seizure thresholds. The purpose of the present study was to test the acute anticonvulsant …
seizure thresholds. The purpose of the present study was to test the acute anticonvulsant …
Methodology matters: Designing a pilot study guided by indigenous epistemologies
SA Juutilainen, M Jeffrey, S Stewart - Human Biology, 2020 - BioOne
Indigenous individuals and communities have experienced historic and ongoing negative
interactions with Western health care and biomedical research. To rebuild trust and mitigate …
interactions with Western health care and biomedical research. To rebuild trust and mitigate …
Framework for evaluating potential causes of health risk factors using average treatment effect and uplift modelling
…, A Nakashook-Zettler, V Costanzo-Alvarez, M Jeffrey… - Algorithms, 2023 - mdpi.com
Acute myeloid leukemia (AML) is a type of blood cancer that affects both adults and children.
Benzene exposure has been reported to increase the risk of developing AML in children. …
Benzene exposure has been reported to increase the risk of developing AML in children. …
Comparative study of five antiepileptic drugs on a translational cognitive measure in the rat: relationship to antiepileptic property
…, N Breysse, E Undzys, DR Derksen, M Jeffrey… - …, 2010 - Springer
Rationale Antiepileptic drugs (AEDs) have been available for many years; yet, new members
of this class continue to be identified and developed due to the limitations of existing drugs, …
of this class continue to be identified and developed due to the limitations of existing drugs, …
A reliable method for intracranial electrode implantation and chronic electrical stimulation in the mouse brain
Background Electrical stimulation of brain structures has been widely used in rodent models
for kindling or modeling deep brain stimulation used clinically. This requires surgical …
for kindling or modeling deep brain stimulation used clinically. This requires surgical …
[HTML][HTML] Traumatic spinal cord injuries among Aboriginal and non-Aboriginal populations of Saskatchewan: a prospective outcomes study
…, S Humphreys, C Rivers, M Jeffrey… - Canadian journal of …, 2020 - ncbi.nlm.nih.gov
Background People of Aboriginal (Indigenous) ancestry are more likely to experience traumatic
spinal cord injury (TSCI) than other Canadians; however, outcome studies are limited. …
spinal cord injury (TSCI) than other Canadians; however, outcome studies are limited. …
Continuous multi-modality brain imaging reveals modified neurovascular seizure response after intervention
D Ringuette, MA Jeffrey, S Dufour… - Biomedical Optics …, 2017 - opg.optica.org
We developed a multi-modal brain imaging system to investigate the relationship between
blood flow, blood oxygenation/volume, intracellular calcium and electrographic activity during …
blood flow, blood oxygenation/volume, intracellular calcium and electrographic activity during …
Multi-modal in vivo imaging of brain blood oxygenation, blood flow and neural calcium dynamics during acute seizures
D Ringuette, MA Jeffrey, PL Carlen… - … ; Neural Imaging and …, 2016 - spiedigitallibrary.org
Dysfunction of the vascular endothelium has been implicated in the development of epilepsy.
To better understand the relation between vascular function and seizure and provide a …
To better understand the relation between vascular function and seizure and provide a …
[BOOK][B] Progesterone and its metabolites: anticonvulsant and behavioral studies
MA Jeffrey - 2014 - search.proquest.com
Progesterone is a well-known anticonvulsant neurosteroid. Progesterone's inhibitory effects
in the brain have long been attributed to its secondary metabolite, 3-α, 5-α-…
in the brain have long been attributed to its secondary metabolite, 3-α, 5-α-…