Older patients with differentiated thyroid cancer exhibit more aggressive pathological characteristics than younger patients

Older patients with differentiated thyroid cancer exhibit more aggressive pathological characteristics than younger patients

Can J Surg 2020;63(1):E69-E70 | PDF

Jasper Johar, MD; Heidi Britton, BSc (Hons); Sam M. Wiseman, MD

Summary

Differentiated thyroid cancer (DTC) has long been recognized as having a worse prognosis in older people. We retrospectively evaluated the clinical and pathological characteristics of 973 sequentially treated patients with primary DTC stratified into 2 age groups, ≥ 55 or < 55 years, based on the current American Joint Committee on Cancer (AJCC) DTC staging system. We found that older patients had a higher frequency of extrathyroidal cancer extension and larger cancers, and that their cancers were less commonly completely resectable.


Accepted July 11, 2019

Acknowledgements: The authors thank Ms. Kaidi Liu, St. Paul’s Hospital Department of Surgery research associate, for her administrative assistance that facilitated the conduct of this study.

Affiliations: From the Department of Surgery St. Paul’s Hospital & University of British Columbia, Vancouver, BC.

Competing interests: None declared.

Contributors: All authors contributed substantially to the conception, writing, and revision of this article and approved the final version for publication.

DOI: 10.1503/cjs.017918

Correspondence to: S.M. Wiseman, Department of Surgery, St. Paul’s Hospital & University of British Columbia, Rm C303, 1081 Burrard St, Vancouver BC V6Z 1Y6, smwiseman@providencehealth.bc.ca