Surrogate end points save lives

Surrogate end points save lives

Surrogate end points save lives

Can J Surg 2017;60(2):81-82 | PDF

Christopher Vinden, MD

Summary

Patient-centric markers are important, and when they can be conveniently measured they should dominate research questions. However, when the research question pertains to serious or potentially fatal illnesses and it will take years or even decades to answer with patient-centric outcomes, then a pragmatic approach based on common sense and surrogate markers should be adopted. This commentary discusses the important role that surrogate markers can play in medical research.


See also the research paper by Adie et al. on page 86.

Accepted Oct. 25, 2016

Affiliations: From the Schulich School of Medicine and Dentistry, Western University, London, Ont.

Competing interests: None declared.

DOI: 10.1503/cjs.013916

Correspondence to: C. Vinden, London Health Sciences Centre, Victoria Hospital, 800 Commissioners Rd E, Rm E2-218, London ON N6A 5W9 chris.vinden@lhsc.on.ca